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Reading Time:. Posted by Matt Terrill. Published at: June 4, When our furry family members become ill and suffer from inflammation, it can be a terrifying experience. Making sure to get them to the vet right away is a surefire way to help, and it can ease a lot of the tension of the unknown! However, you may soon find that other anxieties start to pop up after your veterinary visit.

With so many medications, you might wonder what exactly they are, how they can help, or how adverse effects of new medication could leave your dog feeling worse than before. A common prescription given in veterinary medicine for dogs is a corticosteroid like prednisone or prednisolone. While prednisone and prednisolone are popular in veterinary medication, they still come with some risks that are worth investigating!

Let's break down the uses and serious side effects in dogs of prednisone and prednisolone and explore natural options to help your pets. Prednisone and prednisolone are synthetic glucocorticoids used in a variety of disorders involving inflammatory and autoimmune processes. While prednisone and prednisolone are both are used to treat the same diseases, they are a bit different. Prednisone is what's known as a synthetic corticosteroid, and it's one that might be prescribed by your veterinarian as treatment.

This is also an option used to treat a variety of human illnesses. It's a key medication for bringing down inflammation in pets and humans alike. Prednisone can do a lot for pets, and we'll take a look at how that happens in this article.

Prednisolone is the active metabolite of prednisone. It can cross the cellular membrane and is also used for its anti inflammatory properties. Prednisone and prednisolone are both powerful immunosuppressants that can help the body fight against potentially life-threatening side effects.

However, they should not be used as a treatment for dogs with viral infections. While these drugs can be effective at treating some of the symptoms of a viral infection, they will also suppress the dog's immune system, making them more susceptible to other illnesses. Steroids and corticosteroids are essentially the same. They are artificial drugs, which are made to be similar to the corticosteroids produced naturally in the body. It's important to keep in mind that the drugs prescribed by a doctor like prednisone and prednisolone are not the same as those used illegally.

Prednisone or prednisolone for dogs addresses many issues including their immune system response, metabolism, stress response, and more.

Prednisone is made to replace the naturally-created cortisol when your dog is not feeling well and cannot create enough of the hormone. Cats, however, do not have a strong enough liver to process these drugs and should not take prednisone or prednisolone as medication. Both prednisolone and prednisone are examples of a corticosteroid, so they are both used for the treatment of issues that can create inflammation.

These can also include simply helping to keep your dog's immune system regulated. That said, there is a key difference in how the two options are processed. Prednisone is typically processed in the liver, which allows it to be converted to prednisolone. However, if your dog has liver issues or liver disease of any sort, then a vet will be likely to choose a dose of prednisolone over prednisone for dogs, which can ensure it is easily processed. It's generally not a good idea to make the liver work harder when it's already having problems.

As a result, it's worth looking into prednisolone for dogs with weakened livers. But remember, cats have weaker livers than dogs and prednisone cannot be converted to prednisolone in their small bodies. Typically, professionals recommend that you only use prednisone or prednisolone for dogs on a short-term basis as cortisol replacement. There can be negative consequences associated with long-term steroid use such as liver or kidney disease. The idea is essentially to use enough for it to work, but the smallest amount possible for your dog to avoid serious side effects.

That said, it's important to keep in mind that even a small dose of prednisone on a daily basis can have negative effects. If you're using prednisone for dogs, and your dog hasn't received it before, then it's exceedingly important to keep a close watch on them for negative reactions.

A standard dosage of prednisone and most cortisol at 0. A dosage of around 0. However, it's going to be up to your vet to determine and prescribe prednisone in the correct dosage for your furry friend, as well as guide you through how to help your dog take a dose of prednisone. You'll also want to avoid missing doses, as it can lessen the effect. It's also wise to remember that prednisone shouldn't be used on a long-term basis.

There are other options to seek out if your dog has a hormone deficiency that might require a steroid. Prednisolone and prescribed prednisone for dogs can be used in a number of ways, for a variety of situations. Prednisone and prednisolone are often used to relieve inflammation and swelling, and they can be effective in treating liver dysfunction, spinal cord trauma, and autoimmune diseases such as lupus and autoimmune hemolytic anemia. Prednisone and prednisolone are available both in tablet and liquid forms.

If you're thinking about giving your dog prednisone or prednisolone, talk to your veterinarian first to see if this is the right medication for your pet. There are plenty more uses for prednisone and prednisolone, but typically your veterinarian will know exactly when it should be used, so make sure to heed their advice.

For the most part, prednisone doesn't take long to get working, which is a major convenience. The adrenal glands are supposed to produce steroids on their own, but this disease requires drugs like prednisone or prednisolone to supplement the failing adrenal glands. Just like medications that humans take, side effects in dogs are real, dangerous, and life-threatening. Generally speaking, prednisone for dogs is only prescribed for a short time due to the increased risk of side effects.

While prednisone is generally safe, there are some potential side effects that can occur with long-term use. These include elevated liver enzymes, diabetes mellitus, and allergic reactions. For this reason, prednisone is typically only prescribed for short-term use.

If for any reason your veterinarian may want to use prednisone long-term to treat Addison's Disease, for example, then frequent trips to visit the vet will be needed to make sure it isn't having any serious effects. Pets can also be in danger of itchy skin and vomiting diarrhea. You should also check whether their urination increased over the time they used prednisone and prednisolone.

If you need a deeper understanding of how long pets can remain on prednisone, bring up risks of higher doses and extended time frames with your vet. If your dog is given prednisone, then you'll absolutely want to make sure your vet knows of any other medications that you might give your pet. Otherwise, both prednisolone and prednisone can have some harmful effects and allergic reactions when they are mixed with the wrong drug in high doses. Some common drug interactions include increased risk of gastrointestinal ulcers, high blood pressure, and suppressed immune function.

In addition, keep in mind that prednisone for dogs can cause vaccinations to be less effective. Check with your vet to make sure this doesn't cause problems if you give your dog prednisone. When you're looking for something that can treat your dog with inflammation or other more common issues, there are a lot of natural resources out there that can help.

Check these drug-free options out, and discuss them with your vet to see if they're the right choice for your pet! CBD treatment can be incredible for just about everyone, including your pet. Though it is still a relatively new route in veterinary medicine, scientists are already beginning to explore the benefits a CBD dosage can provide. On top of that, it's completely natural, which means there is an extremely low risk of overdose.

A dose of Innovet's Hemp Dog Treats can help your dog in so many ways, and they find them delicious! In addition, CBD dosage can provide some help to limit the amount of non-natural medications your dog needs.

This product is made to absorb easily and work quickly to both calm current symptoms and may help prevent future pain from occurring. It's truly a great option for inflammation, skin issues, and other immune-mediated diseases. Plus it's a lower-cost option than most medication. CBD is imbued with anti-inflammatory properties but does not suppress the immune system like harsh drugs.

CBD dosage is used to ease illness and disease of many forms in both cats and dogs. CBD treatment is a great veterinarian-approved way to help your dog with stress and anxiety in a highly natural way. It allows you to avoid the side effects of pet anxiety medications and allow your dog to feel calmer at any dosage. Whether it's arthritis, cancer symptoms, skin dermatitis, back pain, or other diseases, it's a great option to leave your pet feeling better without drugs!

While a quick dose of CBD is the top option, there are plenty of other helpful natural resources out there to help out dogs!

The more information you have on your options, the better prepared you'll be when you talk to your veterinarian about alternatives to drugs. These options are also great for cats!

One of the top choices out there is a raw food diet, which allows dogs to eat similarly to what they'd have in the wild. This allows them the greatest potential for natural wound healing and a healthy way to mediate increased appetite. Turmeric is a fantastic option for getting a handle on any inflammation your pet may be experiencing.

There's a good reason it's one of the ingredients in our Hemp Dog Treats. Echinacea is a great drug-free choice for dogs that need some help with their overall immune system. It's all-natural and quite effective. However, it's best to use it off and on, because your dog's body can acclimate to it and stop getting the effects.

As a result, it's ideal for swelling and painful symptoms. Because ginger also has natural anti-inflammatory properties, it cannot suppress the immune system in dogs the way prednisone and prednisolone can. Whether you choose natural solutions or a drug like prednisone and prednisolone, we can all agree that your dog's health is at the top of the priority list. That's why it's extremely important to be armed with information about common medications and the increased risk over natural treatments they can have.

A natural way of healing is absolutely worth trying out, and it can often avoid unpleasant side effects for your beloved dogs and cats. Continue shopping. Close search.

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- Is prednisone safe for dogs



  Veterinarians prescribe prednisone for dogs to treat health conditions resulting from inflammation, such as pain and itching. While generally safe and effective when prescribed by a vet, these drugs can cause an adverse reaction in dogs. Common side effects include vomiting, increased.     ❾-50%}

 

Is prednisone safe for dogs.Prednisone for Dogs: Uses, Side Effects, Dosage, and Drug Interactions You Need to Know



    On top of that, it's completely natural, which means there is an extremely low risk of overdose. When administered, prednisone is processed by the liver and turned into prednisolone. Prednisone is usually given to a dog orally in the form of a pill , but liquid forms are available for smaller dogs or very low doses. Whether it's arthritis, cancer symptoms, skin dermatitis, back pain, or other diseases, it's a great option to leave your pet feeling better without drugs! Prednisone is a synthetic glucocorticoid used to treat many different conditions in many species of animals. It's important to follow your vet's recommendations regarding prednisone dose and administration.

Because prednisone has such a wide range of safe doses, an overdose is unlikely to cause lasting harmful effects in dogs. Dogs that ingest high quantities of prednisone typically experience gastrointestinal distress that revolves as the drug leaves the body. It is possible for high doses of prednisone to cause serious GI ulcers and bleeding. You don't need to panic if your dog accidentally got too much prednisone, but it is important to contact a veterinarian for advice right away.

The vet may tell you to induce vomiting if an extreme amount was ingested. In addition, follow-up supportive care may be needed to manage symptoms. Certain drugs should not be taken in conjunction with prednisone or prednisolone. Other drugs should be used with caution. Be sure to tell your vet about all of your pet's recent medications and supplements. Prednisone has many potential drug interactions, but the most common ones are as follows:.

Pin FB More. In veterinary medicine, prednisone is often prescribed to treat the following conditions:. Inflammation Immune-mediated disorders Addison's disease Allergic reactions Asthma Cancer Skin conditions Shock Central nervous system disorders especially brain and spinal inflammation.

Increased thirst and urination Increased appetite Restlessness Panting Weight gain Vomiting Diarrhea Distended abdomen "pot-belly" appearance Poor haircoat or hair loss Cushing's syndrome Liver dysfunction. If your dog has a chronic condition that requires ongoing care, the costs can quickly add up, which is why many owners try to find a pet insurance plan that covers prescriptions as well.

Prednisone is a prescription steroid used to treat a broad range of conditions in dogs. Many veterinarians prescribe the use of prednisone for dogs as an anti-inflammatory and immune suppressant. Due to these properties of prednisone in dogs, the drug is highly effective at treating conditions such as:.

It may also be used during emergency situations in response to spinal cord trauma, anaphylactic reactions, and several forms of shock. Both drugs are forms of synthetic forms of corticosteroids - a hormone that occurs naturally in canines and humans - however, neither drug is approved by the FDA for animal use. The steroid medication is usually administered orally in the form of tablets and liquid solutions , preferably with food to lower the chance of an upset stomach.

In that case, continue with the schedule as planned because you should never give your dog two doses at once. Some skin conditions, such as dermatitis and hives due to allergies, may be treated with a topical steroid cream. More severe conditions, including anaphylactic shock and Addisonian crisis, may require a steroid injection in a hospital setting. The medication takes effect quickly, usually within one to two hours, and improvement in symptoms should soon follow.

It is important to know that Prednisone should never be stopped abruptly so if your dog is prescribed this medication by a veterinarian you need to follow the instructions carefully. Most veterinarians will prescribe it as a taper course that needs to be followed strictly.

Your vet might monitor your canine companion to ensure that the medication is working properly. Common monitoring practices with these medications include:. The most common side effects of prednisone prednisolone in dogs include increased appetite, increased thirst, and increased urination.

For this reason, prednisone is typically only prescribed for short-term use. If for any reason your veterinarian may want to use prednisone long-term to treat Addison's Disease, for example, then frequent trips to visit the vet will be needed to make sure it isn't having any serious effects. Pets can also be in danger of itchy skin and vomiting diarrhea. You should also check whether their urination increased over the time they used prednisone and prednisolone.

If you need a deeper understanding of how long pets can remain on prednisone, bring up risks of higher doses and extended time frames with your vet. If your dog is given prednisone, then you'll absolutely want to make sure your vet knows of any other medications that you might give your pet. Otherwise, both prednisolone and prednisone can have some harmful effects and allergic reactions when they are mixed with the wrong drug in high doses. Some common drug interactions include increased risk of gastrointestinal ulcers, high blood pressure, and suppressed immune function.

In addition, keep in mind that prednisone for dogs can cause vaccinations to be less effective. Check with your vet to make sure this doesn't cause problems if you give your dog prednisone. When you're looking for something that can treat your dog with inflammation or other more common issues, there are a lot of natural resources out there that can help. Check these drug-free options out, and discuss them with your vet to see if they're the right choice for your pet! CBD treatment can be incredible for just about everyone, including your pet.

Though it is still a relatively new route in veterinary medicine, scientists are already beginning to explore the benefits a CBD dosage can provide. On top of that, it's completely natural, which means there is an extremely low risk of overdose. A dose of Innovet's Hemp Dog Treats can help your dog in so many ways, and they find them delicious! In addition, CBD dosage can provide some help to limit the amount of non-natural medications your dog needs. This product is made to absorb easily and work quickly to both calm current symptoms and may help prevent future pain from occurring.

It's truly a great option for inflammation, skin issues, and other immune-mediated diseases. Plus it's a lower-cost option than most medication. CBD is imbued with anti-inflammatory properties but does not suppress the immune system like harsh drugs. CBD dosage is used to ease illness and disease of many forms in both cats and dogs. CBD treatment is a great veterinarian-approved way to help your dog with stress and anxiety in a highly natural way.

It allows you to avoid the side effects of pet anxiety medications and allow your dog to feel calmer at any dosage. Whether it's arthritis, cancer symptoms, skin dermatitis, back pain, or other diseases, it's a great option to leave your pet feeling better without drugs!

While a quick dose of CBD is the top option, there are plenty of other helpful natural resources out there to help out dogs! The more information you have on your options, the better prepared you'll be when you talk to your veterinarian about alternatives to drugs. These options are also great for cats! One of the top choices out there is a raw food diet, which allows dogs to eat similarly to what they'd have in the wild. This allows them the greatest potential for natural wound healing and a healthy way to mediate increased appetite.

Turmeric is a fantastic option for getting a handle on any inflammation your pet may be experiencing. Clubs Offering: Training Classes. Prednisone for Dogs. By Liz Donovan Nov 07, 1 Minute. Nov 07, 1 Minute.

Health conditions related to inflammation in dogs can result in several unpleasant symptoms, including pain and severe itching. Luckily, there are a few medications that can help with inflammation, two of the most common being prednisolone or prednisone for dogs. But, what's the difference between these two steroids? Although prednisone and prednisolone are two distinct medications, prednisone must be converted into prednisolone by liver enzymes before the drug can work.

Pro Tip: Prescription medications for pets can be quite expensive. If your dog has a chronic condition that requires ongoing care, the costs can quickly add up, which is why many owners try to find a pet insurance plan that covers prescriptions as well. Prednisone is a prescription steroid used to treat a broad range of conditions in dogs. Many veterinarians prescribe the use of prednisone for dogs as an anti-inflammatory and immune suppressant. Due to these properties of prednisone in dogs, the drug is highly effective at treating conditions such as:.

It may also be used during emergency situations in response to spinal cord trauma, anaphylactic reactions, and several forms of shock. Both drugs are forms of synthetic forms of corticosteroids - a hormone that occurs naturally in canines and humans - however, neither drug is approved by the FDA for animal use. The steroid medication is usually administered orally in the form of tablets and liquid solutionspreferably with food to lower the chance of an upset stomach.

In that case, continue with the schedule as planned because you should never give your dog two doses at once. Some skin conditions, such as dermatitis and hives due to allergies, may be treated with a topical steroid cream. More severe conditions, including anaphylactic shock and Addisonian crisis, may require a steroid injection in a hospital setting.

The medication takes effect quickly, usually within one to two hours, and improvement in symptoms should soon follow. It is important to know that Prednisone should never be stopped abruptly so if your dog is prescribed this medication by a veterinarian you need to follow the instructions carefully. Most veterinarians will prescribe it as a taper course that needs to be followed strictly. Your vet might monitor your canine companion to ensure that the medication is working properly.

Common monitoring practices with these medications include:. The most common side effects of prednisone prednisolone in dogs include increased appetite, increased thirst, and increased urination. During long-term use and when the steroid is taken in higher doses for instance, in an emergency setting or for the treatment of autoimmune diseasesside effects can also include diarrhea, vomiting panting, and behavioral changes including aggression.

These medications should be used with caution in dogs with heart disease, diabetes, cataractsosteoporosis, kidney disease, increased blood pressure, and other types of infections.

Prednisone and Prednisolone should also be used cautiously in puppies as they can inhibit growth, as well as in pregnant or nursing dogs. The medications should not be given to dogs that are to undergo allergy testing within the next month. Animals receiving prednisone or prednisolone might be more susceptible to viral and bacterial infections. These drugs can also mask signs of infection, like elevated temperature. Consult your veterinarian about how to taper dogs off prednisone slowly to avoid complications.

Prednisone and prednisolone might r eact with several different medicationsincluding:. If prednisone or prednisolone is used concurrently with other medications prone to causing ulcers, like NSAIDs, the risk of stomach ulcers might increase. Prednisone and prednisolone might also interact with lab testsincluding allergy tests, as well as potassium, urine glucose, cholesterol, and thyroid levels.

Use caution when on a large dosage of prednisone for dogs, as vaccines might be less effective or result in infection. If possible, vaccination should be delayed.

Prednisone and prednisolone might increase insulin requirements in dogs with diabetes. Make sure to let your vet know about any drugs, supplements, or vitamins your dog is taking. A prednisone overdose in dogs can cause itching, weakness, loss of hearing, depression, anxiety, increased blood pressure, heart problems, and seizures. If you suspect your dog has eaten these medications inadvertently or was accidentally overdosed, contact your vet or the Animal Poison Control Center right away.

If possible, bring the prescription container with you when you take your dog for treatment. Liquid forms of the drug should be stored following the label on the bottle. Make sure you keep these and all other medications out of reach of your children and pets. These drugs are not for human use. Pet insurance policies include coverage for medically necessary vet treatments, including diagnostic testing like blood work, x-raysprescription medications, hospitalization, including any treatments while in the hospital, and surgeries.

Realizing the positive financial and medical impact that pet insurance can provide for pet parents and the profession, he lends support and advice to companies like Pawlicy Advisor that simplify the process of connecting with veterinary financing resources.

Skip to content. Keep on reading to learn about the uses, dosage, and side effects of these drugs in dogs. Table of Contents: What is prednisone used for in dogs? Why use prednisolone for dogs instead? What is the right dose of prednisone for dogs? What are the side effects of prednisone for dogs? Risks of prednisone and prednisolone in dogs Potential drug reactions with other medications Can dogs overdose on prednisone?

How to store prednisone and prednisolone Key Takeaways Pro Tip: Prescription medications for pets can be quite expensive. What is prednisone used for in dogs? Common monitoring practices with these medications include: Bloodwork and urinalysis ACTH stimulation tests Blood sugar levels Signs of swelling Appetite and weight changes Potential adverse reactions What are the side effects of prednisone in dogs?

Can dogs overdose on prednisone? Key Takeaways Prednisone and prednisolone are corticosteroid drugs commonly used to treat inflammation, allergies, autoimmune diseases, and some forms of disease.

While generally safe and effective when prescribed by a vet, these drugs can cause an adverse reaction in dogs. Common side effects include vomiting, increased appetite, increased thirst, panting, restlessness, etc. The proper dose of prednisone in dogs will vary depending on several factors, including the medical condition being treated, but owners should always follow the instructions provided by a veterinarian.

If you need more information about these drugs or suspect an accidental overdose, be sure to contact your vet immediately.

More on Dog Medications 5 minute read. More on Dog Insurance 8 minute read. Back to Blog. Pawlicy Advisor is the leading independent marketplace for finding the best coverage for your pet at the lowest rate.

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Veterinarians prescribe prednisone for dogs to treat health conditions resulting from inflammation, such as pain and itching. While generally safe and effective when prescribed by a vet, these drugs can cause an adverse reaction in dogs. Common side effects include vomiting, increased. Prednisone is used for a wide variety of conditions in both dogs and cats. It may be used in emergency situations including anaphylactic reactions. Overall, prednisone is an effective and safe medication that can provide relief for many dogs suffering from a variety of conditions. What are the side effects. Give this medication with food. It can also be given as an injection in the hospital setting. Measure liquid forms carefully. If your pet is on a once daily. We can let your veterinarian know that you are interested in our compounded Prednisone. Polyuria, polydipsia, polyphagia may be seen in dogs even on short-term therapy. Our pet insurance partners. These can include things like:. Dog Name Finder Browse our extensive library of dog names for inspiration.

Ordering patient medications is easy. With an online account, access our extensive formulary or over 40, unique items - 24 hours a day, 7 days a week. Ordering your pet's prescription drugs from Wedgewood Pharmacy is safe, and convenient.

With a prescription number, easily refill prescriptions and enroll in the AutoRefill Program. Log in to fill, refill or renew the medication prescribed by your veterinarian. Commonly prescribed for: Anti-inflammatory. Therapeutic Class: Adrenocorticosteroid Hormone. Prednisone is a synthetic corticosteroid used for many conditions in both human and veterinary medicine.

Its anti-inflammatory activity is approximately four times that of hydrocortisone. Corticosteroids are extremely effective anti-inflammatory drugs because they affect the inflammatory process at so many different levels.

Prednisone is rapidly converted to prednisolone in the liver and, in most instances, these drugs are considered to be roughly equivalent. Corticosteroids have strong beneficial effects but a definite potential to cause negative side-effects if abused. Prednisone may be given by injection, orally, or topically. We can let your veterinarian know that you are interested in our compounded Prednisone. Some states restrict the information we may provide about controlled substances.

Please select your state below. This content is intended for counseling purposes only. No claims are made as to the safety or efficacy of mentioned preparations.

You are encouraged to speak with your prescriber as to the appropriate use of any medication. Use of them does not imply any affiliation with or endorsement by them. About Human Health Careers Contact.

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Call Basic Information Prednisone is a synthetic corticosteroid used for many conditions in both human and veterinary medicine. Dogs and Cats Prednisone is used for a wide variety of conditions in both dogs and cats. It may be used in emergency situations including anaphylactic reactions, spinal cord trauma, and many forms of shock.

It is used to manage and treat immune-mediated disease such as immune-mediated hemolytic anemia or thrombocytopenia, many CNS disorders, some neoplasia, dermatologic diseases, allergic reactions such as asthma, hives and itching, inflammatory orthopedic diseases, endocrine disorders including Addison's Disease, respiratory disease with an inflammatory component, inflammatory bowel diseases, and many other conditions.

Cats may require higher doses than dogs in order to achieve clinical response but they are less likely to develop adverse side-effects. Horses Prednisone is given systemically to decrease inflammatory and immune responses.

Recent work has demonstrated that horses do not absorb oral prednisone although they do absorb oral prednisolone. Other corticosteroids are preferred for intra-articular use. Prednisone Side Effects Systemic side-effects of corticosteroids generally are dependent on dose and duration of treatment. Short-term use of prednisone is unlikely to cause adverse effects.

Adverse effects are more common in animals on immunosuppressive doses. Dogs: Side effects seen in dogs include polyuria, polydipsia, polyphagia, poor hair coat, GI disturbance, diarrhea, vomiting, weight gain, GI ulceration, pancreatitis, lipidemia, elevated liver enzymes, diabetes mellitus, muscle wasting, and possible behavioral changes.

Polyuria, polydipsia, polyphagia may be seen in dogs even on short-term therapy. Cats: Although cats are less likely to develop side effects than dogs, occasionally polyuria, polydipsia, polyphagia, weight gain, GI disturbances, and behavioral changes occur.

Corticosteroids can cause or worsen gastric ulcers. Precautions Chronic or inappropriate use of corticosteroids, including prednisone, can cause life-threatening hormonal and metabolic changes. Adverse effects due to corticosteroid treatment usually occur with long-term administration of the drug, especially when high doses are used. Alternate day therapy with short-acting preparations is preferred. Animals that have received long-term therapy should be withdrawn slowly by tapering the dosage and prolonging the interval between doses.

Corticosteroids suppress immune response. Animals receiving systemic corticosteroids may be more susceptible to bacterial or viral infections. Systemic corticosteroids can mask signs of infection, such as an elevated temperature. Systemic corticosteroids are contraindicated in patients with systemic fungal infections. The treatment of Addison's Disease may be considered an exception.

Prednisone must be converted to prednisolone in the liver. Animals in hepatic failure should receive prednisolone rather than prednisone. Corticosteroids should be avoided or used very carefully in young animals both because of immune suppression and the risk of GI ulcers. Corticosteroids have been implicated as a cause of laminitis in horses and ponies.

Some corticosteroids are thought to be more likely to cause laminitis than others and prednisone historically has not been considered to be in the higher-risk category.

Pony breeds may be more susceptible to developing laminitis than horses. Although corticosteroids may be used in healthy older horses, they should not be used in horses with pituitary pars intermedia dysfunction. These horses already may have high levels of natural corticosteroids and are prone to laminitis and suppressed immune function.

Corticosteroids should be avoided during pregnancy and lactation unless the benefits outweigh the risks.

Large doses in early pregnancy may be teratogenic. Corticosteroids can induce labor and have been used to terminate pregnancy in bitches. Drug Interactions When amphotericin B or diuretics such as furosemide are given with corticosteroids, there is an increased risk of electrolyte imbalances due to calcium and potassium losses.

Digitalis and potassium levels should be monitored closely in animals taking prednisone. Corticosteroids may increase insulin requirements. Estrogen may potentiate the effects of corticosteroids. Drugs that may cause drug interactions with Prednisone include Salicylate, Phenytoin, Phenobarbital, Rifampin, Cyclosporine, Erythromycin, Mitotane and anti-cholinesterase drugs such as Neostigmine and Pyridostigmine.

The immune response to vaccination may be reduced when corticosteroids are given at the same time. The risk of GI ulcers may be increased if corticosteroids and other drugs prone to causing ulcers such as nonsteroidal anti-inflammatory drugs are given at the same time. Looking for Prednisone? Contact my veterinarian. Log in as a practice. Popular Prednisone Dosage Forms. View other Prednisone forms. Barbara Forney is a veterinary practitioner in Chester County, Pennsylvania.

She has a master's degree in animal science from the University of Delaware and graduated from the University of Pennsylvania School of Veterinary Medicine in She began to develop her interest in client education and medical writing in How much will my prescription cost?



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